News and Updates
Keep up with the latest news about the Accelerating Medicines Partnership (AMP®) SCZ program.
(draft) Publication Proposals
Below is a table with AMP SCZ publications currently in progress. To view published AMP SCZ papers, please visit PubMed.
| Proposal Number | Title | Person(s) Proposing the Publication | Keywords | Date |
|---|---|---|---|---|
| 76 | Deconstructing neural heterogeneity in the CHR syndrome: precision mapping of altered excitatory/inhibitory imbalance | Zach Anderson and Vijay A. Mittal | Excitatory/inhibitory implanace, social and role functioning, DTI, fMRI, global functioning scale, | 03/14/2025 |
| 75 | Association of speech heterogeneity and functional connectivity in individuals with clinical high risk for psychosis | Joseph Kambeitz, Annkathrin Böke, Lana Kambeitz-Ilan | Linguistic features, negative symptoms, resting state functional connectivity | 03/14/2025 |
| 74 | Neurophenomenological relationship between self-related experiences in CHR and meditation | Saampras Ganesan and Vanessa Cropley | Default-mode network, fMRI, self-disturbances, meditative awareness-of-self | 03/13/2025 |
| 73 | The neurophenomenology of self-disturbances in CHR | Saampras Ganesan and Vanessa Cropley | Default-mode network, fMRI, self-disturbances, | 03/13/2025 |
| 72 | Baseline Cognitive Functioning in the Accelerating Medicines Partnership Schizophrenia Program: Patterns of Performance across a Diverse International Sample | Kelly Allott and Bill Stone. Other contributors: Walid Yassin, Cassandra Wannan, Ruben Gur, Eve Lewandowski and other Cognition Group Members and DPACC as appropriate. | Cognitive performance, demographics, site factors, negative symptoms, cognitive functining, positive symptoms | 03/13/2025 |
| 71 | Exploring Associations between Suicidality and Attenuated Psychotic Symptoms in Clinical High-Risk for Psychosis | Stefano Damiani, Marika Orlandi, Paolo Fusar-Poli | Attenuated psychotic symptoms, suicidality (ideation and behavior), socio-occupational functioning | 03/13/2025 |
| 70 | Multimodal Neuroimaging and Graph Signal Dynamics in Clinical High Risk States | Yasser Alemán Gómez, Paul Klauser, Philippe Conus, Raoul Jenni, Livia Alerci, Martine Cleusix | Multimodal imaging features, diffusion weighted MRI, resting-state functional MRI, graph signal processing method | 02/26/2025 |
| 68 | Characterising Sleep and Circadian Rhythm Phenotypes in Young People at Clinical High Risk for Psychosis | Rosalind Ge and Vanessa Cropley. Jessica Hartmann, Barnaby Nelson, Justin Baker, Habiballah Rahimi Eichi, other interested AMP SCZ members | Sleep, circadian rhythm, actigraphy, latent profile analysis | 02/06/2025 |
| 67 | Validation of transdiagnostic clinical stages in youth | Rochelle Ruby Ye, Dominic Dwyer, Cassandra Wannan, Isabelle Scott, Barnaby Nelson, Patrick McGorry, Phillip Wolff, Cheryl Corcoran, Guillermo Cecchi, Kelly Allott, Bill Stone, | Transdiagnostic staging, clinical stages | 02/20/2025 |
| 66 | Non-Suicidal Self-Injury in the AMP-SCZ cohort: Prevalence and Demographic and Clinical Correlates | Abigayle Fogarty, Cheryl Corcoran | Non-suicidal self-injury (NSSI), suicidal ideation, suicidal behavior | 01/20/2025 |
| 65 | Capturing Self-Disturbance in Spontaneous Speech_Validation Study Natural Language Analysis in CHR.docx | Powered by Box | Elizabeth Ray, Agrima Srivastava, Zarina Bilgrami, Cheryl Corcoran | Speech validation, natural language analysis | 01/20/2025 |
| 63 | Entry to Clinical Research: Ethnoracial disparities in youth at Clinical High Risk for Psychosis (CHRp) | Bernalyn Ruiz-Yu, Vanessa Calderon, Daisy Lopez, Carrie Bearden | Ethnoracial disparities, social factors, racial/ethnic minorities (REM) | 12/11/2024 |
| 62 | Affective Profiles of Youth at Clinical High Risk for Psychosis | Ian Raugh | Affective features, affective profiles, audio processing | 12/05/2024 |
| 61 | An Overview of Presenting Clinical Symptoms and Functioning in the SCZ AMP Project | Jean Addington | Clinical symptoms, clinical measures, confounding variables, side effects | 12/05/2024 |
| 60 | Reliability and Validity of the Calgary Depression Scale for Schizophrenia (CDSS) in Clinical High-Risk Individuals in the SCZ AMP Study | Jean Addington | Calgary Depression Scale for Schizophrenia (CDSS), major depressive disorder (MDD), negative symptoms | 11/28/2024 |
| 58 | Characterization of White matter abnormalities in subjects at clinical high risk for psychosis using diffusion tensor imaging and free-water imaging | Kang Ik Kevin Cho, PhD and Ofer Pasternak, PhD | White matter abnormalities, diffusion tensor imaging (DTI), free-water imaging (FW), diffusion measures | 10/30/2024 |
| 57 | Broad sequential screening for psychosis risk at the secondary mental health level: Increasing access to evaluation in people at Clinical High Risk | Emily Farina and Scott Woods | Psychosis risk, broad sequential screening, | 11/14/2024 |
| 56 | Clinical Subtype Detection in the CHR Population | John Torous and Andrew (Jin Soo) Byun | Digital biomarkers, digital measures, GPS, accelerometer, screen use, clinical subtypes | 11/06/2024 |
| 55 | Negative Symptoms, Social Cognition, and Suicide Risk in CHR | Aubrey Moe, Nick Breitborde, Heather Wastler | Negative symtpoms, social cognition, suicide risk | 11/06/2024 |
| 54 | Peak Alpha Frequency in the Clinical High Risk | Victor J. Pokorny, Vijay A. Mittal | Peak alpha frequency (PAF), cognitive functioning, social functioning | 11/06/2024 |
| 53 | Machine Learning and Digital Phenotyping to Predict Suicidality in a Clinical High Risk Sample: Baseline Data from AMP SCZ | Alex Dhima, Erlend Lane, John Torous | Digital phenotyping, suicidality, suicide prediction, machine learning, clinical measures | 11/04/2024 |
| 52 | Characterizing grey- and white-matter heterogeneity and stability in CHR individuals using normative modelling | Cassandra Wannan, Dominic Dwyer, Barnaby Nelson, Stephen Wood, Sandra Vieira, Kelly Allott, William Stone, Interested Neuroimaging Working Group Members/other AMP SCZ members | Grey-matter heterogeneity, white-matter heterogeneity, normative neuroimaging, cognition | 11/04/2024 |
| 51 | Structural MRI Motion Estimation with Deep Learning | Sylvain Bouix, Charles Bricout (MSc student), Ofer Pasternak, Michael Harms, Kevin Cho, Owen Borders | MRI, deep learning, motion estimation, visual QC prediction | 10/18/2024 |
| 50 | Prevalence of general medical conditions in individuals at clinical high risk for psychosis and its association with symptoms and functioning | Beier Yao, Eve Lewandowski, John Torous | General medical conditions, clinical symptoms, social functioning | 09/27/2024 |
| 49 | Digital phenotyping of sleep in the CHR population | John Torous, Andrew (Jin Soo) Byun | Digital phenotyping, sleep, sleep patterns, actigraphy, clinical meausres | 09/27/2024 |
| 48 | Objective Sleep Midpoint Estimation from Phone Sensor Data: A predictor of Depressive Episodes | Habib Rahimi Eichi, Yoon Chung, Justin Baker | Sleep, temporal locus of sleep, sleep estimation, sleep patterns, depressive episodes | 09/27/2024 |
| 47 | Predicting Elevated Negative Affective States from Smartphone Sensors in Clinical High-Risk Individuals: Personalized Machine Learning Approach. | Yoonho Chung, Habib Rahimi Eichi, Justin Baker | Machine learning, personalized prediction, negative affective states | 09/23/2024 |
| 46 | Actigraphy-based Individualized Energy Imbalance Association with Negative Affect | Habib Rahimi Eichi, Yoon Chung, Justin Baker | Mood oscillations, affective disorders, physical activity, sleep, actigraphy | 09/23/2024 |
| 45 | Prediction of Affective and Psychotic Symptoms Using Smartphone-Based EMA Survey and Phone Sensor in Individuals at Clinical High-Risk. | Yoonho Chung, Habib Rahimi Eichi, Justin Baker | Clinical symptoms, affective symptoms, psychotic symptoms, smartphone data analysis | 09/23/2024 |
| 44 | Investigating Missingness Patterns in EMA and Passive Sensor Data | Yoonho Chung, Habib Rahimi Eichi, Justin Baker, John Torous, Ofer Pasternak | Participant engagement, missingness, clinical symptoms | 09/23/2024 |
| 43 | Identifying the structural and effective connectivity measures differentiating people at clinical high risk for psychosis from healthy controls | Elise Rowe, Barnaby Nelson, Stephen Wood, Suzie Lavoie, Thomas Whitford, Dan Mathalon | Effective connectivity, functional connectivity, structural connectivity, white matter integrity, sensory information integration network, auditory attention network, visual attention network | 09/13/2024 |
| 42 | Protocol for Improving Smartphone Data Quality in a Longitudinal, International Multisite Study: Efforts from AMP SCZ. | Erlend Lane, Jane Mikkelson, Matt Flathers, John Torous | Digital phenotyping, data quality, smartphone data analysis, passive data | 09/11/2024 |
| 41 | Modification of the Family Interview for Genetic Studies (FIGS) for AMP® Schizophrenia | Sinead Kelly, Diana Perkins | Family Interview for Genetic Studies (FIGS), methods development, tool development, rater training, scoring algorithm | 09/11/2024 |
| 40 | Interim Characterization of Multimodal Outcome Measures from The Accelerating Medicines Partnership Schizophrenia Baseline Data | Johanna Seitz-Holland, Nora Penzel, Ofer Pasternak | Multimodal analysis, primary outcome measures, measure characterization, baseline analysis | 09/09/2024 |
| 39 | Combining Large Language Models and Feedback From Clinical High Risk Individuals To Identify Features of Lived Experience Narratives | Jenna Reinen | Symptom-related aspects, large language model (LLM), natural language processing (NLP), feature identification, lived experience narrative | 08/16/2024 |
| 38 | Automatic Assessment of the Scale of Prodromal Symptoms (SOPS) Using Large Language Models | Carla Agurto | Scale of Prodromal Symptoms (SOPS), large language model (LLM), speech assessment, speech analysis | 08/14/2024 |
| 37 | Understanding Cognitive Heterogeneity and its Link with Neural Activity Patterns in Clinical High-Risk Patients: Implications for Treatment | Michael Sand | Cognition, EEG, neural activity patterns | 07/30/2024 |
| 36 | Incidence, Prevalence, and Stability of Remission over Time in Individuals at CHR for Psychosis | Ofer Pasternak, Marty Shenton | Remission, positive symptoms | 07/28/2024 |
| 35 | Replicating and extending relationships between premorbid adjustment, symptoms, and cognition in clinical high risk for psychosis | Henery R. Cowan, Vijay A. Mittal | Premorbid Adjustment Scale (PAS), cognition, negative symptoms, positive symptoms, anxiety, depression | 07/26/2024 |
| 34 | Uncovering Cognitive and Neuroanatomical Differences: Investigation of the Impact of Childhood Trauma on Healthy and At-risk for Psychosis Individuals in the Context of Adverse Life Events | Oznur Basturk, Lana Kambeitz-Ilankovic | Childhood trauma, cognition, adverse life events, neuroanatomical differences | 07/03/2024 |
| 33 | Elucidating the association between symptoms, cognition and functioning using longitudinal network analysis of digital markers in individuals at clinical high risk for psychosis | Julian Wenzel,Hannah Hacker, Lana Kambeitz-Ilankovic, Joseph Kambeitz | Digital biomakers, digital measures, geolocation, cognition, social functioning, social interactions | 07/03/2024 |
| 32 | Baseline Severity of General Psychopathology in Youth at Clinical High-Risk for Psychosis Worldwide: Cross-Cultural Evidence from the Accelerating Medicines Partnership (AMP) Schizophrenia (SCZ) Program and Comparison with Previous Cohorts | Gabriele Lo Buglio | Psychopathology, cross-cultural differences | 05/30/2024 |
| 31 | The Effects of Childhood Trauma and Adversity on Social Cognition and Functioning in Individuals at a Clinical High Risk of Psychosis | Julia Szacilo | Childhood trauma, adversity, cognition, social functioning | 05/20/2024 |
| 30 | Concordance of SIPS and CAARMS Criteria for CHR and Symptom Significance Classification in the Positive Symptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS (PSYCHS) | Alyssa Bathery | Structured Interview for Psychosis Risk Symptoms (SIPS), Comprehensive Assessment of At-Risk Mental States (CAARMS), clinical significance, measure concordance, measure disagreement, symptom classification | 05/06/2024 |
| 29 | The association between sleep quality and quantity and clinical high-risk status | Johanna Seitz-Holland | Sleep, sleep patterns, actigraphy, symptom severity | 05/19/2024 |
| 28 | The impact of cannabis legalization on the association between cannabis use and attenuated psychotic symptoms – results from the worldwide AMP SCZ study | Nora Penzel, Sinead M. Kelly | Cannabis, cannabis legalization, symptom severity, global functioning | 04/10/2024 |
| 27 | Preliminary Psychometric Properties of the 15 items of the Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS | Catalina Mourgues | Structured Interview for Psychosis Risk Symptoms (SIPS), Comprehensive Assessment of At-Risk Mental States (CAARMS), positive symptoms, convergent validity, divergent validity, item discrimination | 03/27/2024 |
| 26 | A shift to female preponderance in a recent sample of individuals at a clinical high risk for psychosis (CHR-P) | Emily Farina | Female preponderance, gender differences, symptom severity, social functioning | 03/27/2024 |
| 25 | Examining the impact of neighborhood factors and experienced discrimination on psychosis symptoms and functioning among marginalized young adults | Jason Schiffman | Environmental risk factors, discrimination, symptom severity, social functioning | 04/16/2024 |
| 24 | Neural Signatures of Hallucination Emergence in a Clinical High-Risk Population | Al Powers | Hallucinations, delusions, multimodal analysis | 02/26/2024 |
| 22 | Examining a Hierarchical Taxonomy of Symptoms for Individuals at CHR | Trevor Williams | Hierarchical dimensional model, psychopathology | 02/14/2024 |
| 21 | Longitudinal Psychometric Validation of the Negative Symptom Inventory- Psychosis Risk (NSI-PR) in AMP SCZ | Gregory Strauss, Vijay Mittal | Negative Symptom Inventory-Psychosis Risk (NSI-PR), longitudinal psychometric validation, validation | 02/14/2024 |
| 20 | Exploring the clinical and functional correlates of childhood trauma in Clinical High Risk for psychosis patients | Luis Alameda | Childhood trauma, adversity, psychopathology, functional domains, depression, positive symptoms, environmental risk factors | 02/14/2024 |
| 19 | Predictive Modelling of Future Suicidal Ideation and Attempts in Clinical High Risk Population using Machine Learning | Josh Nguyen | Suicide prediction model, validation, model development, machine learning, suicidal ideation, suicidality | 02/21/2024 |
| 18 | Social and Role Functioning in the AMP SCZ Study: Description and correlates | Ricardo E Carrion, Barbara Cornblatt | Social functioning, role functioning, rater accuracy, convergent validity, discriminant validity | 02/21/2024 |
| 17 | Assessment of the stability and repeatability of speech features and their relationship with clinical measures. | Simon Hartmann, Isabelle Scott | Speech, linguistic features, acoustic features, speech reliability, positive symptoms, negative symptoms, thought disorder | 11/29/2023 |
| 16 | Suicide Risk in CHR: Relationship with Symptoms, Stress and Sleep | Heather Wastler, Nicholas Breitborde, Aubrey Moe, Lexi Blouin | Suicide, suicidality, sleep, stress, clinical symptoms | 11/29/2023 |
| 15 | The Effect of Cognition on Real-World Functioning for Individuals at Clinical High-Risk for Psychosis | Danielle N. Pratt, Vijay Mittal | Cognition, processing speed, verbal learning, global functioning, verbal memory, IQ | 11/29/2023 |
| 11 | Strategies for Collecting Language Samples to Forecast the Onset of Psychosis in Clinical High-Risk Individuals | Zarina R. Bilgrami, Michaela Ennis, Einat Liebenthal, Eduardo Castro, Carla Agurto, Justin T. Baker, Barnaby Nelson, Guillermo A. Cecchi, Cheryl M. Corcoran, Phillip Wolff | Language analysis, language collection methodologies, behavioral data, acoustic analysis | 06/28/2023 |
| 10 | Body fluid biomarkers and psychosis risk in AMP-SCZ: Design considerations | Diana Perkins and Scott Clark | Fluid biomarkers, blood and saliva analysis, metadata collection | 06/28/2023 |
| 9 | Electroencephalography-based event-related potential and event-related oscillation assessments in the AMP SCZ Study | Daniel Mathalon | EEG-based biomarkers, EEG hardware, EEG analysis, test-retest reliability | 06/28/2023 |
| 6 | Digital Team Protocol Paper: Title TBD | John Torous | Digital biomarkers, digital measures, actigraphy, protocol development, behavioral features, data quality | 06/20/2023 |
Last Reviewed on May 8, 2025