Standard Operating Procedures (SOPs)

The following SOPs are used in the AMP SCZ program to acquire measures/assessments for ~2500 participants over a 2 year period as described in the study design:

Cognitive Measures
This document describes the SOPs to acquire cognitive measures for each participant at five time points – first at baseline, then at two, six, 12 and 24 months after study entry.

EEG Acquisition
This document describes the SOPs to acquire EEG for each participant at two time points – first at baseline and second at two months after study entry.

Fluid Biomarker
This document describes the SOPs to acquire fluid biomarkers (blood, saliva) for each participant at two time points – first at baseline and second at two months after study entry.

Actigraphy
This document describes the SOPs to acquire actigraphy data for each participant on a daily basis.

Ecological Momentary Assessment (EMA) and Passive Sensing (PS)
This document describes the SOPs used to acquire Digital Health data – both EMA and PS – for each participant on a daily basis.

Language Sample Acquisition
This document describes the SOPs to acquire language/free speech samples for each participant at two time points – first at baseline and second at two months after study entry.

Clinical Data Acquisition
This document describes the SOPs to acquire clinical data for each participant at every time point – starting at screening and continuing through all twelve study visits.